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How Taken: Ciprofloxacin may be taken with or without food. Ciprofloxacin is partially metabolized by the liver and excreted by the kidney. Dosages require adjustment in patients with severely abnormal liver or kidney function. Antacids block the absorption of ciprofloxacin and they should not be taken together. For uncomplicated urinary tract infections, Cipro can be given twice daily for three days while Proquin XR can be given once daily for three days.

Drug Class and Mechanism: Many common infections in humans are caused by single cell organisms, called bacteria. Bacteria can grow and multiply, infecting different parts of the body. Medicines that control and eradicate these bacteria are called antibiotics. Ciprofloxacin is an antibiotic that stops multiplication of bacteria by inhibiting the reproduction and repair of their genetic material (DNA).

Missed Dose: Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

Warnings Precautions: Avoid prolonged exposure to sunlight. Ciprofloxacin may increase the sensitivity of the skin to sunlight, and a sunburn may result. If sun exposure is unavoidable, wear protective clothing and use a sunscreen. Call your doctor if you experience severe burning, redness, itching, rash, or swelling after exposure to the sun. Use caution when driving, operating machinery, or performing other hazardous activities. Ciprofloxacin may cause dizziness. If you experience dizziness, avoid these activities. Avoid excessive consumption of products that contain caffeine. Ciprofloxacin may increase the effects of caffeine. Ciprofloxacin, administered together with theophylline, can lead to elevated blood levels of theophylline. Theophylline is used to open airways in the treatment of asthma. Toxic levels of theophylline can lead to seizures, and disturbances in heart rhythm. If concurrent use of ciprofloxacin and theophylline cannot be avoided, frequent blood tests to monitor theophylline blood levels are performed. Ciprofloxacin should be used with caution in patients with central nervous system diseases such as seizures, because rare seizures have been reported in patients, receiving this medication. Ciprofloxacin should be avoided in children and adolescents under 18 years old, as safe use in these patients have not been established. Many antibiotics, including ciprofloxacin, can alter the normal bacteria in the colon and encourage overgrowth of a bacteria, responsible for the development of inflammation of the colon (pseudomembranous colitis). Pseudomembranous colitis can cause fever, abdominal pain, diarrhea, and sometimes even shock. Patients taking ciprofloxacin can develop sensitivity of the skin to direct sunlight. Ciprofloxacin can enhance the action of the anticoagulant warfarin (Coumadin), and increase the risk of bleeding. Ciprofloxacin should be avoided in pregnancy, as safe use in these patients have not been established. Ciprofloxacin should be avoided in nursing mothers, as safe use in these patients have not been established.

Storage: Ciprofloxacin should be stored at below 86 degrees F.

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